Healthcare, Life Sciences & Medical Office Construction — Nationwide
From multi-tenant MOBs to cGMP cleanrooms, TCG delivers healthcare and life sciences construction across 38 states — including design-build, specialized MEP, infection control compliance, and medical equipment coordination.
Healthcare & Life Sciences Cost Estimator
Describe your medical, pharmaceutical, or life sciences project and get a preliminary construction cost estimate powered by TCG.ai — the same engine behind our general construction estimator.
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Include details about facility type, specialty, procedure rooms, imaging, cleanroom requirements, regulatory standards, and location.
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Your Construction Cost Estimate
Healthcare, Life Sciences & MOB Construction
Healthcare construction is among the most highly regulated, technically complex, and schedule-sensitive sectors in commercial building. Medical facilities must meet FGI Guidelines for room sizing and clearances, ASHRAE 170 for healthcare ventilation, NFPA 101 life safety requirements, ADA accessibility, and state health department licensing standards — all while maintaining infection control during construction in occupied facilities.
At Terrapin Construction Group (TCG), healthcare and life sciences construction is delivered through our integrated design-build model — combining architectural design, MEP engineering, preconstruction, and construction management under a single contract. This is especially critical in healthcare where MEP systems (medical gas, HVAC pressurization, emergency power) represent 30%–50% of total construction cost.
For pharmaceutical and life sciences projects, TCG provides IMP installation for cleanroom envelopes, equipment procurement for process and lab systems, and coordination with commissioning and validation teams to meet FDA cGMP and ISO 14644 requirements.
How TCG Builds Healthcare & Life Sciences Facilities
TCG's design-build delivery integrates every phase from regulatory pre-planning through commissioning.
Regulatory & Feasibility
State health department consultation, FGI compliance mapping, CMS certification path, infection control risk assessment (ICRA), and early cost benchmarking via preconstruction.
Design & Engineering
Architectural design per FGI and ADA. MEP engineering for medical gas, ASHRAE 170 ventilation, emergency power, and nurse call/low-voltage systems.
Structure & Shell
Steel, concrete, or wood-frame construction per IBC. For labs and cleanrooms: IMP envelope from PermaTherm or Kingspan for controlled environments.
Medical MEP & Specialty
Medical gas piping (O2, N2O, vacuum, air), HEPA filtration, pressurization cascades, radiation shielding for imaging, NFPA 99 health care facilities code compliance.
Equipment & Finishes
Medical equipment procurement and installation — imaging, sterilization, casework, dental chairs. Healthcare flooring (sheet vinyl, epoxy, rubber).
Commissioning & Certification
HVAC balancing, medical gas certification per ASSE 6010, cleanroom validation per ISO 14644, state licensing inspections, CMS survey coordination. TCG's owner's rep ensures sign-off.
Healthcare & Life Sciences Facilities We Build
TCG has construction experience across the full healthcare and life sciences spectrum.
Healthcare Codes, Standards & Industry Organizations
Healthcare construction is governed by a complex web of federal, state, and industry-specific standards that go far beyond standard commercial building codes.
FGI Guidelines
The Facility Guidelines Institute publishes the definitive standards for healthcare facility design — room sizes, clearances, medical gas, ventilation, and infection control requirements adopted by most states.
fgiguidelines.org →ASHRAE 170
ASHRAE Standard 170 specifies ventilation rates, pressure relationships, temperature, and humidity for healthcare spaces — the primary HVAC design standard for medical facilities.
ashrae.org →NFPA 99
NFPA 99 Health Care Facilities Code covers medical gas systems, electrical systems, emergency power, and fire protection specifically for healthcare occupancies.
nfpa.org →FDA cGMP
FDA 21 CFR Parts 210/211 govern pharmaceutical manufacturing facility design — cleanroom classification, HVAC validation, material flow, and contamination control.
fda.gov →ISO 14644
ISO 14644 defines cleanroom classification standards (ISO 5–8) that govern particle counts, air changes, HEPA filtration, and environmental monitoring for pharmaceutical and biotech facilities.
iso.org →CMS / Medicare
The Centers for Medicare & Medicaid Services sets conditions of participation that directly impact facility design — influencing everything from corridor widths to nurse station sight lines.
cms.gov →ADA
ADA Standards for Accessible Design are especially stringent in healthcare — covering exam table transfer, accessible diagnostic equipment, parking, and restroom clearances.
ada.gov →NFPA 101 Life Safety
NFPA 101 has healthcare-specific chapters governing smoke compartments, suite arrangements, means of egress, and defend-in-place strategies for patient care areas.
nfpa.org →ICC / IBC
The International Building Code provides base structural, fire-resistance, and occupancy requirements for Institutional (I-2) and Business (B) occupancy healthcare buildings.
iccsafe.org →AAMI / Sterilization
The Association for the Advancement of Medical Instrumentation publishes sterilization and sterile processing standards that shape SPD (sterile processing department) design and MEP.
aami.org →USP 797 / 800
USP Chapter 797 (sterile compounding) and USP 800 (hazardous drug handling) dictate cleanroom design, air handling, and containment for compounding pharmacies.
usp.org →OSHA
OSHA regulates healthcare worker safety including bloodborne pathogens, hazardous drug exposure, radiation safety, and ergonomic requirements for clinical environments.
osha.gov →Healthcare & Life Sciences Case Studies
Vision Source MOB — Sugarland, TX
Multi-specialty ophthalmology and optometry clinic with exam lanes, pre-testing, optical dispensary, and minor procedure room. Full design-build delivery with MEP engineering.
Bellaire Dental — Houston, TX
High-end dental office buildout with 8 operatories, digital imaging, sterilization center, and patient amenities. General contracting with integrated equipment procurement.
65,000 SF Pharma Cleanroom — Northeast
cGMP cleanroom facility with PermaTherm IMP envelope, ISO 7 classification, FDA validation-ready design. TCG served as Owner's Rep.
NREL Research Facility — Golden, CO
Laboratory and research facility construction for the National Renewable Energy Laboratory. Specialized MEP systems and construction management.
How Much Does Healthcare Construction Cost?
Healthcare construction costs vary significantly by facility type and clinical complexity. Basic medical office space (exam rooms, admin) runs $200–$350/SF. Specialty MOBs with procedure rooms and imaging run $300–$500/SF. Ambulatory surgery centers run $400–$650/SF. Pharmaceutical cleanrooms range from $350–$800+/SF depending on ISO classification.
The primary cost drivers in healthcare are MEP systems (medical gas, HVAC pressurization, emergency power — typically 30%–50% of total cost), radiation shielding for imaging suites, infection control finishes, and regulatory compliance documentation. FGI Guidelines mandate minimum room sizes and clearances that directly impact the building footprint and cost.
Use our AI estimator above for a project-specific range, or schedule a meeting with our preconstruction team. Also explore our general estimator or IMP estimator.
Explore TCG's Full Construction Platform
Frequently Asked Questions
Browse common questions about healthcare construction, or contact TCG. Visit our general FAQ for more.
Basic MOB: $200–$350/SF. Specialty with procedures/imaging: $300–$500/SF. ASC: $400–$650/SF. Cleanrooms: $350–$800+/SF. Use our AI estimator or general estimator.
ISO 8: $350–$500/SF. ISO 7: $450–$650/SF. ISO 5: $600–$1,000+/SF. Key drivers: HEPA filtration, pressurization, IMP envelope, and FDA cGMP validation requirements.
MOB TI: 4–8 months. Ground-up MOB: 10–16 months. ASC: 12–18 months. Cleanroom: 14–24 months. Design-build compresses by 15–30%.
IBC, NFPA 101/99, FGI Guidelines, ASHRAE 170, ADA, state health department licensing. Pharma adds FDA cGMP and ISO 14644.
The Facility Guidelines Institute publishes the primary reference standard for healthcare facility design — room sizes, clearances, medical gas, ventilation, and infection control — adopted by most state health departments.
Yes — BSL-1/2 labs, pharma cleanrooms (ISO 5–8), compounding pharmacies (USP 797/800), and research facilities. Our IMP installation and MEP engineering are critical for these specialized envelopes and HVAC systems.
Yes — across 38 states with offices in Denver, Houston, Albany, and Sheridan. See our project portfolio.
Let's Build Your Next Healthcare or Life Sciences Facility
From multi-tenant MOBs to cGMP cleanrooms, TCG's integrated construction platform delivers compliant, high-performance healthcare environments — on time, on budget, in all 38 states.
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